ctcRbase

Entry Detail

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General Information

Database ID: SKCM05822 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MTRR Full Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Category: mRNA Synonyms: MSR|cblE Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 7851186 End Site(bp): 7906025 Gene Summary: This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000124275 HGNC ID: HGNC:7473 Entrez Gene: 4552

Expression Profile of MTRR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-96-5p YES YES NO Display: