ctcRbase

Entry Detail

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General Information

Database ID: SKCM05838 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MRPS2 Full Name: mitochondrial ribosomal protein S2 Category: mRNA Synonyms: CGI-91|COXPD36|MRP-S2|S2mt Chromosome: chr9 Strand: + Coordinate: Start Site(bp): 135499984 End Site(bp): 135504673 Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] External Links: Ensembl ID: ENSG00000122140 HGNC ID: HGNC:14495 Entrez Gene: 51116

Expression Profile of MRPS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-497-5p YES YES NO Display: