ctcRbase

Entry Detail

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General Information

Database ID: SKCM05866 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TIMP3 Full Name: TIMP metallopeptidase inhibitor 3 Category: mRNA Synonyms: HSMRK222|K222|K222TA2|SFD Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 32801701 End Site(bp): 32863043 Gene Summary: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000100234 HGNC ID: HGNC:11822 Entrez Gene: 7078

Expression Profile of TIMP3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1197 YES NO YES hsa-miR-136-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES NO YES hsa-miR-147a YES NO NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-206 YES NO YES hsa-miR-21-5p YES YES YES hsa-miR-219a-5p YES YES NO hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-299-3p YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-329-3p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-384 YES NO YES hsa-miR-425-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-452-5p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-590-5p YES YES YES hsa-miR-613 YES NO YES hsa-miR-642a-5p YES NO NO hsa-miR-665 YES NO YES hsa-miR-873-5p YES YES NO Display: