ctcRbase

Entry Detail

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General Information

Database ID: SKCM05986 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ARHGEF9 Full Name: Cdc42 guanine nucleotide exchange factor 9 Category: mRNA Synonyms: COLLYBISTIN|EIEE8|HPEM-2|PEM-2|PEM2 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 63634967 End Site(bp): 63809274 Gene Summary: The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. This brain-specific protein also acts as an adaptor protein for the recruitment of gephyrin and together these proteins facilitate receceptor recruitement in GABAnergic and glycinergic synapses. Defects in this gene are the cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy, as well as several other types of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017] External Links: Ensembl ID: ENSG00000131089 HGNC ID: HGNC:14561 Entrez Gene: 23229

Expression Profile of ARHGEF9 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-147a YES NO NO hsa-miR-154-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-599 YES YES NO Display: