Entry Detail



General Information

Database ID:SKCM06060
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SLC25A14
Full Name:solute carrier family 25 member 14
Category:mRNA
Synonyms:BMCP1|UCP5
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):130339888End Site(bp):130373361
Gene Summary:Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013]
External Links:
Ensembl ID:ENSG00000102078
HGNC ID:HGNC:10984
Entrez Gene:9016



Expression Profile of SLC25A14 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A