ctcRbase

Entry Detail

---



General Information

Database ID: SKCM06077 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NUMA1 Full Name: nuclear mitotic apparatus protein 1 Category: mRNA Synonyms: NMP-22|NUMA Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 72002864 End Site(bp): 72080693 Gene Summary: This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] External Links: Ensembl ID: ENSG00000137497 HGNC ID: HGNC:8059 Entrez Gene: 4926

Expression Profile of NUMA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-130a-3p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-873-5p YES YES NO Display: