ctcRbase

Entry Detail

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General Information

Database ID: SKCM06119 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TMX3 Full Name: thioredoxin related transmembrane protein 3 Category: mRNA Synonyms: PDIA13|TXNDC10 Chromosome: chr18 Strand: - Coordinate: Start Site(bp): 68673688 End Site(bp): 68715298 Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017] External Links: Ensembl ID: ENSG00000166479 HGNC ID: HGNC:24718 Entrez Gene: 54495

Expression Profile of TMX3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-122-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-375 YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-433-3p YES YES YES hsa-miR-450a-5p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-93-5p YES YES YES Display: