ctcRbase

Entry Detail

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General Information

Database ID: SKCM06125 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TBCK Full Name: TBC1 domain containing kinase Category: mRNA Synonyms: HSPC302|IHPRF3|TBCKL Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 106041599 End Site(bp): 106321495 Gene Summary: This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] External Links: Ensembl ID: ENSG00000145348 HGNC ID: HGNC:28261 Entrez Gene: 93627

Expression Profile of TBCK Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-155-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-876-5p YES YES NO Display: