ctcRbase

Entry Detail

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General Information

Database ID: SKCM06231 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GPSM2 Full Name: G protein signaling modulator 2 Category: mRNA Synonyms: CMCS|DFNB82|LGN|PINS Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 108875350 End Site(bp): 108934545 Gene Summary: The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] External Links: Ensembl ID: ENSG00000121957 HGNC ID: HGNC:29501 Entrez Gene: 29899

Expression Profile of GPSM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-582-5p YES NO YES Display: