ctcRbase

Entry Detail

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General Information

Database ID: SKCM06340 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SHROOM2 Full Name: shroom family member 2 Category: mRNA Synonyms: APXL|HSAPXL Chromosome: chrX Strand: + Coordinate: Start Site(bp): 9786456 End Site(bp): 9949443 Gene Summary: This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] External Links: Ensembl ID: ENSG00000146950 HGNC ID: HGNC:630 Entrez Gene: 357

Expression Profile of SHROOM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-136-5p YES YES NO hsa-miR-137 YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-24-3p YES YES YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-9-5p YES NO YES Display: