ctcRbase

Entry Detail

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General Information

Database ID: SKCM06353 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TINF2 Full Name: TERF1 interacting nuclear factor 2 Category: mRNA Synonyms: DKCA3|TIN2 Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 24239643 End Site(bp): 24242674 Gene Summary: This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010] External Links: Ensembl ID: ENSG00000092330 HGNC ID: HGNC:11824 Entrez Gene: 26277

Expression Profile of TINF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-139-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-495-3p YES YES NO Display: