ctcRbase

Entry Detail

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General Information

Database ID: SKCM06395 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ARHGEF12 Full Name: Rho guanine nucleotide exchange factor 12 Category: mRNA Synonyms: LARG|PRO2792 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 120336914 End Site(bp): 120489936 Gene Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000196914 HGNC ID: HGNC:14193 Entrez Gene: 23365

Expression Profile of ARHGEF12 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-1297 YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-195-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199a-5p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-199b-5p YES NO YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-21-5p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-219a-5p YES NO YES hsa-miR-22-3p YES NO YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-361-5p YES NO YES hsa-miR-362-5p YES NO YES hsa-miR-370-3p YES NO YES hsa-miR-375 YES NO YES hsa-miR-383-5p YES NO YES hsa-miR-424-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES NO YES hsa-miR-497-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES YES hsa-miR-625-5p YES NO NO hsa-miR-96-5p YES NO YES Display: