ctcRbase

Entry Detail

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General Information

Database ID: SKCM06407 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PHC2 Full Name: polyhomeotic homolog 2 Category: mRNA Synonyms: EDR2|HPH2|PH2 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 33323623 End Site(bp): 33431052 Gene Summary: In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000134686 HGNC ID: HGNC:3183 Entrez Gene: 1912

Expression Profile of PHC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-150-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-155-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-191-5p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-22-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-296-5p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-331-3p YES NO YES hsa-miR-335-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-665 YES NO YES Display: