ctcRbase

Entry Detail

---



General Information

Database ID: SKCM06465 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ACACB Full Name: acetyl-CoA carboxylase beta Category: mRNA Synonyms: ACC2|ACCB|HACC275 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 109116595 End Site(bp): 109268226 Gene Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000076555 HGNC ID: HGNC:85 Entrez Gene: 32

Expression Profile of ACACB Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-497-5p YES YES YES Display: