ctcRbase

Entry Detail

---



General Information

Database ID: SKCM06751 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MID1 Full Name: midline 1 Category: mRNA Synonyms: BBBG1|FXY|GBBB1|MIDIN|OGS1|OS|OSX|RNF59|TRIM18|XPRF|ZNFXY Chromosome: chrX Strand: - Coordinate: Start Site(bp): 10445310 End Site(bp): 10833654 Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016] External Links: Ensembl ID: ENSG00000101871 HGNC ID: HGNC:7095 Entrez Gene: 4281

Expression Profile of MID1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-122-5p YES YES NO hsa-miR-124-3p YES NO YES hsa-miR-1271-5p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES NO YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-506-3p YES NO YES hsa-miR-519d-3p YES YES YES hsa-miR-542-3p YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-758-3p YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-96-5p YES YES NO Display: