Entry Detail



General Information

Database ID:SKCM06774
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SETD2
Full Name:SET domain containing 2
Category:mRNA
Synonyms:HBP231|HIF-1|HIP-1|HSPC069|HYPB|KMT3A|LLS|SET2|p231HBP
Chromosome:chr3
Strand:-
Coordinate:
Start Site(bp):47016429End Site(bp):47163967
Gene Summary:Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
External Links:
Ensembl ID:ENSG00000181555
HGNC ID:HGNC:18420
Entrez Gene:29072



Expression Profile of SETD2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-128-3p
YES
YES
NO
hsa-miR-142-5p
YES
NO
YES
hsa-miR-146a-5p
YES
YES
NO
hsa-miR-146b-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
YES
hsa-miR-23b-3p
YES
YES
YES
hsa-miR-296-3p
YES
YES
NO
hsa-miR-369-3p
YES
NO
YES
hsa-miR-374a-5p
YES
YES
YES
hsa-miR-374b-5p
YES
YES
YES
hsa-miR-410-3p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-655-3p
YES
NO
YES
hsa-miR-873-5p
YES
YES
NO
hsa-miR-876-5p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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