ctcRbase

Entry Detail

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General Information

Database ID: SKCM07050 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SCD5 Full Name: stearoyl-CoA desaturase 5 Category: mRNA Synonyms: ACOD4|FADS4|HSCD5|SCD2|SCD4 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 82629539 End Site(bp): 82798857 Gene Summary: Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008] External Links: Ensembl ID: ENSG00000145284 HGNC ID: HGNC:21088 Entrez Gene: 79966

Expression Profile of SCD5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-137 YES YES NO hsa-miR-141-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-21-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-342-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-487b-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-93-5p YES YES YES Display: