Entry Detail



General Information

Database ID:SKCM07155
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ITIH5
Full Name:inter-alpha-trypsin inhibitor heavy chain family member 5
Category:mRNA
Synonyms:ITI-HC5|PP14776
Chromosome:chr10
Strand:-
Coordinate:
Start Site(bp):7559270End Site(bp):7666998
Gene Summary:This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
External Links:
Ensembl ID:ENSG00000123243
HGNC ID:HGNC:21449
Entrez Gene:80760



Expression Profile of ITIH5 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A