ctcRbase

Entry Detail

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General Information

Database ID: SKCM07191 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MAP3K11 Full Name: mitogen-activated protein kinase kinase kinase 11 Category: mRNA Synonyms: MEKK11|MLK-3|MLK3|PTK1|SPRK Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 65597755 End Site(bp): 65615382 Gene Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000173327 HGNC ID: HGNC:6850 Entrez Gene: 4296

Expression Profile of MAP3K11 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-138-5p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-145-5p YES NO YES hsa-miR-150-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-485-5p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-542-3p YES YES YES hsa-miR-760 YES NO YES hsa-miR-93-5p YES YES YES Display: