ctcRbase

Entry Detail

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General Information

Database ID: SKCM07263 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GPHN Full Name: gephyrin Category: mRNA Synonyms: GEPH|GPH|GPHRYN|HKPX1|MOCODC Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 66507407 End Site(bp): 67181803 Gene Summary: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000171723 HGNC ID: HGNC:15465 Entrez Gene: 10243

Expression Profile of GPHN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-138-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-190a-5p YES YES YES hsa-miR-190b YES YES YES hsa-miR-194-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-299-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-375 YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-96-5p YES YES YES Display: