Entry Detail



General Information

Database ID:SKCM07394
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PNPLA8
Full Name:patatin like phospholipase domain containing 8
Category:mRNA
Synonyms:IPLA2-2|IPLA2G|MMLA|PNPLA-gamma|iPLA2gamma
Chromosome:chr7
Strand:-
Coordinate:
Start Site(bp):108470422End Site(bp):108569666
Gene Summary:This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]
External Links:
Ensembl ID:ENSG00000135241
HGNC ID:HGNC:28900
Entrez Gene:50640



Expression Profile of PNPLA8 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-21-5p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-34a-5p
YES
YES
NO
hsa-miR-34c-5p
YES
YES
NO
hsa-miR-375
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-449a
YES
YES
NO
hsa-miR-449b-5p
YES
YES
NO
hsa-miR-7-5p
YES
YES
NO
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