ctcRbase

Entry Detail

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General Information

Database ID: SKCM07415 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MED7 Full Name: mediator complex subunit 7 Category: mRNA Synonyms: ARC34|CRSP33|CRSP9 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 157137412 End Site(bp): 157159019 Gene Summary: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000155868 HGNC ID: HGNC:2378 Entrez Gene: 9443

Expression Profile of MED7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-519d-3p YES YES NO hsa-miR-613 YES YES NO hsa-miR-93-5p YES YES NO Display: