ctcRbase

Entry Detail

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General Information

Database ID: SKCM07497 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MNT Full Name: MAX network transcriptional repressor Category: mRNA Synonyms: MAD6|MXD6|ROX|bHLHd3 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 2384060 End Site(bp): 2401118 Gene Summary: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000070444 HGNC ID: HGNC:7188 Entrez Gene: 4335

Expression Profile of MNT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-128-3p YES YES NO hsa-miR-1321 YES NO NO hsa-miR-139-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-185-5p YES NO NO hsa-miR-195-5p YES NO YES hsa-miR-210-3p YES YES NO hsa-miR-214-3p YES NO NO hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-24-3p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-423-5p YES NO NO hsa-miR-424-5p YES NO YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-503-5p YES NO NO hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-520f-3p YES NO YES hsa-miR-541-3p YES NO NO hsa-miR-654-5p YES NO NO Display: