ctcRbase

Entry Detail

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General Information

Database ID: SKCM07500 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PREX1 Full Name: phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Category: mRNA Synonyms: P-REX1 Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 48624252 End Site(bp): 48827883 Gene Summary: The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000124126 HGNC ID: HGNC:32594 Entrez Gene: 57580

Expression Profile of PREX1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-206 YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-218-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-369-3p YES NO NO hsa-miR-374a-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-410-3p YES YES YES hsa-miR-411-5p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-613 YES YES YES hsa-miR-873-5p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES YES Display: