ctcRbase

Entry Detail

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General Information

Database ID: SKCM07554 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ATP2A2 Full Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Category: mRNA Synonyms: ATP2B|DAR|DD|SERCA2 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 110280756 End Site(bp): 110351093 Gene Summary: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008] External Links: Ensembl ID: ENSG00000174437 HGNC ID: HGNC:812 Entrez Gene: 488

Expression Profile of ATP2A2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-137 NO YES YES hsa-miR-141-3p YES YES YES hsa-miR-142-3p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-149-5p YES YES YES hsa-miR-151a-3p YES NO YES hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-24-3p YES NO YES hsa-miR-25-3p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-32-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-491-5p YES NO NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES YES hsa-miR-541-3p YES NO NO hsa-miR-654-5p YES NO NO hsa-miR-655-3p YES NO YES hsa-miR-744-5p YES NO NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-98-5p YES YES YES Display: