| ncRNA Symbol: | GGA2 | | Full Name: | golgi associated, gamma adaptin ear containing, ARF binding protein 2 | | Category: | mRNA | | Synonyms: | VEAR | | Chromosome: | chr16 | | Strand: | - | | Coordinate: | | Start Site(bp): | 23463542 | End Site(bp): | 23521995 | | | Gene Summary: | This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008] | | External Links: | |
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