ctcRbase

Entry Detail

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General Information

Database ID: SKCM07732 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EXOC6 Full Name: exocyst complex component 6 Category: mRNA Synonyms: EXOC6A|SEC15|SEC15L|SEC15L1|SEC15L3|Sec15p Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 92834713 End Site(bp): 93059493 Gene Summary: The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA). Alternative splicing and the use of alternative promoters results in multiple transcript variants. A paralogous gene encoding a similar protein is present on chromosome 2. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000138190 HGNC ID: HGNC:23196 Entrez Gene: 54536

Expression Profile of EXOC6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-758-3p YES YES NO Display: