ctcRbase

Entry Detail

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General Information

Database ID: SKCM07832 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: LRBA Full Name: LPS responsive beige-like anchor protein Category: mRNA Synonyms: BGL|CDC4L|CVID8|LAB300|LBA Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 150264531 End Site(bp): 151015727 Gene Summary: The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] External Links: Ensembl ID: ENSG00000198589 HGNC ID: HGNC:1742 Entrez Gene: 987

Expression Profile of LRBA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-140-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-9-5p YES YES YES Display: