ctcRbase

Entry Detail

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General Information

Database ID: SKCM07889 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: KIAA0100 Full Name: KIAA0100 Category: mRNA Synonyms: BCOX|BCOX1|CT101|FMP27 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 28614440 End Site(bp): 28645454 Gene Summary: This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017] External Links: Ensembl ID: ENSG00000007202 HGNC ID: HGNC:28960 Entrez Gene: 9703

Expression Profile of KIAA0100 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-193a-5p YES NO YES hsa-miR-328-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-874-3p YES YES NO hsa-miR-875-5p YES YES NO Display: