ctcRbase

Entry Detail

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General Information

Database ID: SKCM07938 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BCL6 Full Name: BCL6, transcription repressor Category: mRNA Synonyms: BCL5|BCL6A|LAZ3|ZBTB27|ZNF51 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 187721377 End Site(bp): 187745727 Gene Summary: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] External Links: Ensembl ID: ENSG00000113916 HGNC ID: HGNC:1001 Entrez Gene: 604

Expression Profile of BCL6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-17-5p YES NO YES hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-339-5p YES YES YES hsa-miR-346 YES YES YES hsa-miR-362-3p YES YES NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES NO YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-543 YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-93-5p YES NO YES hsa-miR-9-5p YES YES YES Display: