ctcRbase

Entry Detail

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General Information

Database ID: SKCM07943 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SOX6 Full Name: SRY-box 6 Category: mRNA Synonyms: HSSOX6|SOXD Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 15966449 End Site(bp): 16739591 Gene Summary: This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] External Links: Ensembl ID: ENSG00000110693 HGNC ID: HGNC:16421 Entrez Gene: 55553

Expression Profile of SOX6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p NO YES YES hsa-miR-1271-5p YES YES YES hsa-miR-137 YES YES YES hsa-miR-1-3p YES NO YES hsa-miR-15a-5p NO YES YES hsa-miR-15b-5p NO YES YES hsa-miR-16-5p NO YES YES hsa-miR-182-5p YES NO YES hsa-miR-194-5p NO YES YES hsa-miR-195-5p NO YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-206 YES NO YES hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES NO YES hsa-miR-21-5p NO YES YES hsa-miR-23a-3p NO YES YES hsa-miR-23b-3p NO YES YES hsa-miR-300 YES NO NO hsa-miR-376c-3p NO YES YES hsa-miR-378a-3p NO YES YES hsa-miR-381-3p YES NO NO hsa-miR-422a NO YES YES hsa-miR-424-5p NO YES YES hsa-miR-433-3p YES YES NO hsa-miR-489-3p YES NO YES hsa-miR-497-5p NO YES YES hsa-miR-499a-5p YES NO YES hsa-miR-505-3p NO YES YES hsa-miR-590-5p NO YES YES hsa-miR-613 YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-96-5p YES YES YES Display: