ctcRbase

Entry Detail

---



General Information

Database ID: SKCM07958 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: UNG Full Name: uracil DNA glycosylase Category: mRNA Synonyms: DGU|HIGM4|HIGM5|UDG|UNG1|UNG15|UNG2 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 109097574 End Site(bp): 109110992 Gene Summary: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] External Links: Ensembl ID: ENSG00000076248 HGNC ID: HGNC:12572 Entrez Gene: 7374

Expression Profile of UNG Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-195-5p YES NO YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-424-5p YES NO YES hsa-miR-448 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-497-5p YES NO YES Display: