| ncRNA Symbol: | ALKBH2 | | Full Name: | alkB homolog 2, alpha-ketoglutarate dependent dioxygenase | | Category: | mRNA | | Synonyms: | ABH2 | | Chromosome: | chr12 | | Strand: | - | | Coordinate: | | Start Site(bp): | 109088188 | End Site(bp): | 109093631 |
| | Gene Summary: | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008] | | External Links: | |
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