ctcRbase

Entry Detail

---



General Information

Database ID: SKCM08172 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FANCA Full Name: FA complementation group A Category: mRNA Synonyms: FA|FA-H|FA1|FAA|FACA|FAH|FANCH Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 89737549 End Site(bp): 89816657 Gene Summary: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000187741 HGNC ID: HGNC:3582 Entrez Gene: 2175

Expression Profile of FANCA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-140-3p YES NO YES hsa-miR-140-5p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-199a-5p YES NO YES hsa-miR-199b-5p YES NO YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-28-5p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-324-5p YES YES YES hsa-miR-335-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-370-3p NO YES YES hsa-miR-422a YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-503-5p YES YES YES hsa-miR-542-3p YES YES NO hsa-miR-708-5p YES YES NO Display: