Entry Detail



General Information

Database ID:SKCM08199
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ARHGEF1
Full Name:Rho guanine nucleotide exchange factor 1
Category:mRNA
Synonyms:GEF1|LBCL2|LSC|P115-RHOGEF|SUB1.5
Chromosome:chr19
Strand:+
Coordinate:
Start Site(bp):41883161End Site(bp):41930150
Gene Summary:Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000076928
HGNC ID:HGNC:681
Entrez Gene:9138



Expression Profile of ARHGEF1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
YES
hsa-miR-125a-5p
YES
YES
YES
hsa-miR-125b-5p
YES
YES
YES
hsa-miR-143-3p
YES
NO
YES
hsa-miR-185-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
YES
hsa-miR-200c-3p
YES
NO
YES
hsa-miR-429
YES
YES
YES
hsa-miR-506-3p
YES
YES
NO
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