Entry Detail



General Information

Database ID:SKCM08233
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:WARS2
Full Name:tryptophanyl tRNA synthetase 2, mitochondrial
Category:mRNA
Synonyms:NEMMLAS|TrpRS
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):119031216End Site(bp):119140671
Gene Summary:Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000116874
HGNC ID:HGNC:12730
Entrez Gene:10352



Expression Profile of WARS2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
YES
hsa-let-7b-5p
YES
YES
YES
hsa-let-7c-5p
YES
YES
YES
hsa-let-7d-5p
YES
YES
YES
hsa-let-7e-5p
YES
YES
YES
hsa-let-7f-5p
YES
YES
YES
hsa-let-7g-5p
YES
YES
YES
hsa-let-7i-5p
YES
YES
YES
hsa-miR-122-5p
YES
YES
NO
hsa-miR-124-3p
YES
YES
NO
hsa-miR-128-3p
YES
YES
NO
hsa-miR-136-5p
YES
YES
NO
hsa-miR-137
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-146a-5p
YES
YES
NO
hsa-miR-146b-5p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-22-3p
YES
YES
YES
hsa-miR-296-3p
YES
YES
NO
hsa-miR-31-5p
YES
YES
NO
hsa-miR-320a
YES
YES
YES
hsa-miR-320b
YES
YES
YES
hsa-miR-320c
YES
YES
YES
hsa-miR-320d
YES
YES
YES
hsa-miR-326
YES
YES
YES
hsa-miR-330-5p
YES
YES
YES
hsa-miR-361-5p
YES
YES
NO
hsa-miR-487b-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-9-5p
YES
YES
YES
hsa-miR-98-5p
YES
YES
YES
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