ctcRbase

Entry Detail

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General Information

Database ID: SKCM08236 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FKBP5 Full Name: FKBP prolyl isomerase 5 Category: mRNA Synonyms: AIG6|FKBP51|FKBP54|P54|PPIase|Ptg-10 Chromosome: chr6 Strand: - Coordinate: Start Site(bp): 35573585 End Site(bp): 35728583 Gene Summary: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] External Links: Ensembl ID: ENSG00000096060 HGNC ID: HGNC:3721 Entrez Gene: 2289

Expression Profile of FKBP5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-100-5p YES YES YES hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-122-5p YES NO YES hsa-miR-129-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-17-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-195-5p YES NO YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES NO YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-300 YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-342-3p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-375 YES NO YES hsa-miR-376c-3p YES YES YES hsa-miR-378a-3p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-422a YES YES YES hsa-miR-423-5p YES NO YES hsa-miR-424-5p YES NO YES hsa-miR-495-3p YES YES YES hsa-miR-497-5p YES NO YES hsa-miR-499a-5p YES YES YES hsa-miR-519d-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-874-3p YES NO YES hsa-miR-876-5p YES YES NO hsa-miR-877-5p YES NO YES hsa-miR-93-5p YES YES NO hsa-miR-99a-5p YES YES YES hsa-miR-99b-5p YES YES YES Display: