Entry Detail



General Information

Database ID:SKCM08245
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GRK6
Full Name:G protein-coupled receptor kinase 6
Category:mRNA
Synonyms:GPRK6
Chromosome:chr5
Strand:+
Coordinate:
Start Site(bp):177403204End Site(bp):177442901
Gene Summary:This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000198055
HGNC ID:HGNC:4545
Entrez Gene:2870



Expression Profile of GRK6 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1271-5p
YES
YES
YES
hsa-miR-137
YES
YES
YES
hsa-miR-1-3p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-184
YES
YES
NO
hsa-miR-19a-3p
YES
YES
YES
hsa-miR-19b-3p
YES
YES
YES
hsa-miR-206
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-613
YES
YES
NO
hsa-miR-96-5p
YES
YES
YES
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