ctcRbase

Entry Detail

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General Information

Database ID: SKCM08249 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NBPF3 Full Name: NBPF member 3 Category: mRNA Synonyms: AE2 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 21440128 End Site(bp): 21485005 Gene Summary: This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. DUF1220 copy number variations in human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Feb 2013] External Links: Ensembl ID: ENSG00000142794 HGNC ID: HGNC:25076 Entrez Gene: 84224

Expression Profile of NBPF3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-9-5p YES YES NO Display: