ctcRbase

Entry Detail

---



General Information

Database ID: SKCM08255 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TRIM25 Full Name: tripartite motif containing 25 Category: mRNA Synonyms: EFP|RNF147|Z147|ZNF147 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 56887909 End Site(bp): 56914038 Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000121060 HGNC ID: HGNC:12932 Entrez Gene: 7706

Expression Profile of TRIM25 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-197-3p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-873-5p YES NO YES hsa-miR-876-5p YES YES NO hsa-miR-9-5p YES YES NO Display: