Entry Detail



General Information

Database ID:SKCM08266
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MGAT2
Full Name:mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Category:mRNA
Synonyms:CDG2A|CDGS2|GLCNACTII|GNT-II|GNT2
Chromosome:chr14
Strand:+
Coordinate:
Start Site(bp):49620795End Site(bp):49623481
Gene Summary:The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000168282
HGNC ID:HGNC:7045
Entrez Gene:4247



Expression Profile of MGAT2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-155-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-186-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
YES
hsa-miR-200c-3p
YES
YES
YES
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-375
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-429
YES
YES
YES
hsa-miR-487b-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
YES
hsa-miR-496
YES
YES
YES
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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