Entry Detail



General Information

Database ID:SKCM08355
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MYO9B
Full Name:myosin IXB
Category:mRNA
Synonyms:CELIAC4|MYR5
Chromosome:chr19
Strand:+
Coordinate:
Start Site(bp):17075781End Site(bp):17214537
Gene Summary:This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
External Links:
Ensembl ID:ENSG00000099331
HGNC ID:HGNC:7609
Entrez Gene:4650



Expression Profile of MYO9B Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-133a-3p
YES
YES
YES
hsa-miR-133b
YES
YES
YES
hsa-miR-154-5p
YES
YES
NO
hsa-miR-192-5p
YES
YES
NO
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-215-5p
YES
YES
NO
hsa-miR-338-3p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-542-3p
YES
YES
NO
hsa-miR-582-5p
YES
NO
YES
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