ctcRbase

Entry Detail

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General Information

Database ID: SKCM08447 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CYTH3 Full Name: cytohesin 3 Category: mRNA Synonyms: ARNO3|GRP1|PSCD3|cytohesin-3 Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 6161776 End Site(bp): 6272644 Gene Summary: This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000008256 HGNC ID: HGNC:9504 Entrez Gene: 9265

Expression Profile of CYTH3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-140-3p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-153-3p YES NO YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-205-5p YES YES NO hsa-miR-22-3p YES YES YES hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-323a-3p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-370-3p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-374a-5p YES NO YES hsa-miR-374b-5p YES NO YES hsa-miR-384 YES YES NO hsa-miR-421 YES YES NO hsa-miR-429 YES YES YES hsa-miR-448 YES YES YES hsa-miR-452-5p YES NO YES hsa-miR-485-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-599 YES YES NO hsa-miR-665 YES NO YES hsa-miR-7-5p YES YES YES hsa-miR-9-5p YES NO YES hsa-miR-98-5p YES NO YES Display: