ctcRbase

Entry Detail

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General Information

Database ID: SKCM08599 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ASB7 Full Name: ankyrin repeat and SOCS box containing 7 Category: mRNA Synonyms: - Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 100602534 End Site(bp): 100651705 Gene Summary: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000183475 HGNC ID: HGNC:17182 Entrez Gene: 140460

Expression Profile of ASB7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-139-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-142-3p YES YES YES hsa-miR-153-3p YES YES YES hsa-miR-15a-5p NO YES YES hsa-miR-15b-5p NO YES YES hsa-miR-16-5p NO YES YES hsa-miR-186-5p NO YES YES hsa-miR-195-5p NO YES YES hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-206 YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-224-5p NO YES YES hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-340-5p NO YES YES hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-424-5p NO YES YES hsa-miR-448 YES NO YES hsa-miR-495-3p YES YES YES hsa-miR-497-5p NO YES YES hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES NO hsa-miR-875-5p YES NO YES Display: