ctcRbase

Entry Detail

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General Information

Database ID: SKCM08614 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DENND1A Full Name: DENN domain containing 1A Category: mRNA Synonyms: FAM31A|KIAA1608 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 123379654 End Site(bp): 123930152 Gene Summary: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010] External Links: Ensembl ID: ENSG00000119522 HGNC ID: HGNC:29324 Entrez Gene: 57706

Expression Profile of DENND1A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-96-5p YES YES NO Display: