Entry Detail



General Information

Database ID:SKCM08642
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:KCNQ5
Full Name:potassium voltage-gated channel subfamily Q member 5
Category:mRNA
Synonyms:Kv7.5|MRD46
Chromosome:chr6
Strand:+
Coordinate:
Start Site(bp):72621792End Site(bp):73198851
Gene Summary:This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
External Links:
Ensembl ID:ENSG00000185760
HGNC ID:HGNC:6299
Entrez Gene:56479



Expression Profile of KCNQ5 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-181a-5p
NO
YES
YES
hsa-miR-181b-5p
NO
YES
YES
hsa-miR-181c-5p
NO
YES
YES
hsa-miR-181d-5p
NO
YES
YES
hsa-miR-19a-3p
NO
YES
YES
hsa-miR-19b-3p
NO
YES
YES
hsa-miR-370-3p
NO
YES
YES
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