ctcRbase

Entry Detail

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General Information

Database ID: SKCM08678 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PTPRG Full Name: protein tyrosine phosphatase, receptor type G Category: mRNA Synonyms: HPTPG|PTPG|R-PTP-GAMMA|RPTPG Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 61561569 End Site(bp): 62297613 Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000144724 HGNC ID: HGNC:9671 Entrez Gene: 5793

Expression Profile of PTPRG Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-196a-5p NO YES YES hsa-miR-196b-5p NO YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-206 YES YES YES hsa-miR-208a-3p YES YES YES hsa-miR-208b-3p YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p NO YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-361-5p YES NO YES hsa-miR-362-3p NO YES YES hsa-miR-369-3p YES NO NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-499a-5p YES YES YES hsa-miR-613 YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-802 YES NO YES Display: