ctcRbase

Entry Detail

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General Information

Database ID: SKCM08680 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: UBTF Full Name: upstream binding transcription factor Category: mRNA Synonyms: CONDBA|NOR-90|UBF|UBF-1|UBF1|UBF2 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 44205033 End Site(bp): 44221626 Gene Summary: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000108312 HGNC ID: HGNC:12511 Entrez Gene: 7343

Expression Profile of UBTF Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-145-5p YES NO YES hsa-miR-186-5p YES NO NO hsa-miR-28-5p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-342-3p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-370-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES YES hsa-miR-410-3p YES NO YES hsa-miR-485-5p YES YES YES hsa-miR-486-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-541-3p YES NO NO hsa-miR-542-3p YES YES NO hsa-miR-654-5p YES NO NO hsa-miR-708-5p YES YES NO hsa-miR-873-5p YES YES NO Display: