ctcRbase

Entry Detail

---



General Information

Database ID: SKCM08708 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TRIB3 Full Name: tribbles pseudokinase 3 Category: mRNA Synonyms: C20orf97|NIPK|SINK|SKIP3|TRB3 Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 362835 End Site(bp): 397559 Gene Summary: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000101255 HGNC ID: HGNC:16228 Entrez Gene: 57761

Expression Profile of TRIB3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-132-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-182-5p YES NO YES hsa-miR-192-5p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-219a-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-96-5p YES YES YES Display: