ncRNA Symbol: | MAF1 | Full Name: | MAF1 homolog, negative regulator of RNA polymerase III | Category: | mRNA | Synonyms: | - | Chromosome: | chr8 | Strand: | + | Coordinate: | Start Site(bp): | 144104499 | End Site(bp): | 144107611 | | Gene Summary: | This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008] | External Links: | |
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