Entry Detail



General Information

Database ID:SKCM08715
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MAF1
Full Name:MAF1 homolog, negative regulator of RNA polymerase III
Category:mRNA
Synonyms:-
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):144104499End Site(bp):144107611
Gene Summary:This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000179632
HGNC ID:HGNC:24966
Entrez Gene:84232



Expression Profile of MAF1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
NO
YES
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-107
YES
NO
YES
hsa-miR-122-5p
YES
YES
YES
hsa-miR-148a-3p
YES
YES
YES
hsa-miR-148b-3p
YES
YES
YES
hsa-miR-152-3p
YES
YES
YES
hsa-miR-17-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-224-5p
YES
YES
YES
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-370-3p
YES
YES
NO
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